Prevalence of viral hepatitis in patients attending medical camp

Objective of this study was to check prevalence of Viral Hepatitis in Patients attending Medical Camp Cross sectional study. This study was conducted in free Medical Camp of Shaheed Mohtarma Benazir Bhutto Medical University Larkana from 01.07.2011 to 31.12.2011. An advertisement was given one week prior via media for awareness of people. The camp was organized by the faculty of Medical unit III on 1[st] July 2011. This camp, apart from necessary medicines, equipped with diagnostic facilities to diagnose hepatitis B and C viruses. Patients willing to participate in this study were enrolled; patients with known hepatitis B and C were excluded. ELISA technique was used to diagnose. This study was approved by Ethical committee of Shaheed Mohtrama Benazir Bhutto Medical University. SPSS version 19 was used for data analysis. Total of 400 peoples were seen at the camp, 96 of them were already known cases of hepatitis B and C and were excluded from analysis. Of 304 patients 246 were males and 154 were females. From 304 patients 32 [10.5%] patients had hepatitis C and 16 [5.3%] had hepatitis B and rest were seronegative. The frequency of HCV and HBV was common in patients with age between 20 to 40 years. This was a small effort to increase awareness in local population regarding the course of viral hepatitis. We also collected data regarding present prevalence of chronic viral hepatitis in rural areas of interior Sindh. Much more is to be done to control this misery of our community

Comparative study between intranasal antrstomy and antral lavage an experience at CMCH Larkana

To compare the results of intranasal asntrostomy and antral lavage in maxillary sinusitis. This randomized control study was conducted in the department of ENT Chandka Medical College Hospital Larkana during the period from December 2004 to 2007. The overall study of 150 cases was conducted. Out of 150 cases 92 [61.31%] were male and 58 [38.71%] were female and the male / female ratio was 1.6:1. Symptomatology was dominated by PND 95% purulent rhinorrhea 70% headache 52% and nasal obstruction 25%. The overall result of 150 patients x-ray showing mucosal theckining 89 [59.3%] hazzy / opaque sinus 40 [26.6%] and fluid level 14 [9.4%] three times antral lavage was done in all 100 patients. Out of 100 patients 33 got no benefit and underwent for intranasal asntrostomy along with selected 50 patients. Every patient was followed up for 2 weeks. Antral lavage showed 67% benefit and 33% patients got no benefit while intranasal antrstomy followed up patients got 90% benefit and 10% got no benefit This study shows that results of intranal antrstomy is better than antral lavage

Pancytopenia; study of 40 patients at cmc hospital larkana

Pancytopenia is said to exist in an adult when the hemoglobin level is less than 13.5gm/dl in males and 1l.5gm/dl in females, white cell count less than 4x10[9]L[1] and platelet count less than 150x10[9]/L[1]. The causes of pancytopenia are aplastic anemia, subleukemic leukemia, myelodysplasia [2] multiple myeloma, nutritional deficiencies leading to megaloblastic anemia, hypersplenism, paroxysmal nocturnal hemoglobinuria, AIDS, infections such as miliary tuberculosis, leishmaniasis, brucellosis etc. To determine the frequency of various causes of pancytopenia in gender at Chandka Medical College, Larkana. Cross Sectional Study. OPD and Medical Ward-ll, Chandka Medical College Hospital Larkana. 01 years study from February 2007 to February 2008. Patients of either sex, who attended medical ward-ll of Chandka Medical College Hospital Larkana, either as inpatient or out patient department, from February 2007 to February 2008 and fulfilled the inclusion criteria, were included in this study. Pancytopenia was considered as hemoglobin value less than 13.5gm/dl in males or 11.5gm/dl in females, a white cell count less than 4x10[9]/L and Platelets count less than 150x10[9]/L. Patients of less than 12 years and pregnant females were excluded from the study. Out of 40 patients, 29 [72.5%] were males and 11 [27.5%] were females. Female to male ratio was 1:2.6. The mean ages of males were 29.10 +/- 16.46 years whereas of females 36.14 +/- 15.6 years [P = 0.22]. Aplastic anemia was the most common pathology encountered and was diagnosed in 13 cases [31.5%], followed by hypersplenism 09 [22.9%], Megaloblastic anemia 06 [15%] and hodgkin's lymphoma in 04 [10%] cases. Other less common causes detected were multiple myeloma 02 [5%], drug induced 02 [5%] and malaria, milliary tuberculosis, myelodysplastic syndrome, emophagocytic syndrome was 01 [2.5%] case in each. We concluded that aplastic anemia was the most common cause in our patients and more than 2/3rd patients were young males. We think the causes of aplastic anemia in this study may be misuse of drugs, kushtas, exposure to chemicals and viral infections

Prevalence of hepatitis-C virus infection in Khairpurnathan Shah and Shahdakot: a city based screening program

The world health Organization estimates that approximately 3% of the world population is infected with hepatitis-C virus [HCV] and there are more than 170 million individuals with chronic HCV infection who are at risk of developing liver cirrhosis, decompensated liver disease and hepatocellular carcinoma while in Pakistan according to a safe estimate, approximately 10 million people are infected with HCV. To observe the prevalence of HCV infection in our remote areas and to find out the possible causes for the spread of HCV infection, among the individual of Khairpur Nathan Shah and Shahdadkot. One day city based HCV screening program was conducted in the two cities i.e. Khairpur Nathan Shah and Shahdadkot. Cable and papers were used to invite subjects to come in for free HCV screening. The over all seropositivity among 406 subjects was 30.29%. The prevalence of HCV infection was higher in males [76.1% as compared to females [23.9%] and it was highest in subjects between 31-40 years of age [34.2%]. In this city based screening program, we found a high prevalence of HCV infection among the residents of Khairpur Nathan Shah and Shahdadkot. Broader based studies for HCV screening program are suggested in the remote areas of Pakistan

Frequency of gallstones in type II diabetes mellitus

To determine the frequency and factors predisposing patients with type-Il diabetes mellitus to gallstones disease. Case-control study. Medical and surgical OPD, Chandka Medical College Hospital Larkana from January 2007 to December 2007. Total no: of 200 patients with one hundred diabetes mellitus type-2 with gallstones and one hundred age gender matched controls were taken. All the patients were examined for body mass index, waist hip ratio and investigated for blood sugar levels and lipid profile and pan abdomen ultrasound. Fifteen percent of diabetic patients had ultrasound evidence of gallstones as compared to 7% in non diabetic controls. There was significant increase in frequency of gallstones in diabetic patient's increasing age with peak incidence in seventh decade i.e. 60-69 years, and decline in 8th decade i.e. 70-79 years. The average age of diabetic patients with gallstones disease, was significantly higher than without gallstones disease. [p=-00 1]. The mean duration of disease in diabetic patients with gallstones disease was 5.0+ 4.8 years compared with 4.5+ 3.5 years in diabetic patients without gallstones disease [P=0.722]. The mean serum cholesterol and triglycerides levels 4.3.3 mmol/L and 1.5+ 0.8 mmol/L respectively in the diabetic patients with gallstones disease was higher than those without gallstones disease was higher than those without gallstones disease 3.4:f 0.5 mmol/L [P=0.0941] and 1.4 +/- 0.7 mmol/L [p=0-712] respectively, the mean body mass index with diabetic patients with gallstones disease was 26.2+ 5.5 kg/m2 compared with 25.7 +/- 6.7 kg/m2 in those without gallstones disease The frequency of gallstones disease in diabetes mellitus type II increasing with age female gender, obese hyperlipidemia and longer duration of disease